There are many consideration to be make.
- Synergy between your party
- Your enemies’ weaknesses
- To complete world puzzle/riddle
You can deal a considerable of burst damage by initiating elemental reaction. For instance, you can make electrocharge by applying electro into wet enemies. Enemies are wet by standing in the water, drenched by rain or attacked by water infused skill.
There are some enemies that have elemental shield protecting them, such as elemental mage, fatui and etc. You will need to produce elemental reaction to their shield to quickly break it.
You also need to swap around your characters in order to comple the world puzzle, such as burning torches or activating some elemental totem.